Midtown East Hotel Reservations

Affordable style at the Seton Hotel

Book your Midtown East Hotel stay with the Seton, just steps from Grand Central Terminal, nestled in New York City’s Midtown East neighborhood. Our stylish and affordable accommodations are located at 144 E 40th St., between Lexington & 3rd Avenues.Make the Seton your first choice in NYC Midtown Hotels.